Important Clinical Notes for Patient Discussions

• The "45-Day Refill Rule" for Foundayo: For cash-paying patients utilizing the manufacturer's savings card, maintaining the $299 price on the highest maintenance doses (14.5 mg and 17.2 mg) requires refilling the prescription within 45 days of the prior fill. Missing this window causes the cash price for those specific high doses to revert to $349.

• Oral Ingestion Differences: The primary differentiator between the two pill options is administration. While oral Wegovy requires a strict fasting window to ensure absorption, Foundayo is a non-peptide small molecule, meaning it is absorbed efficiently regardless of food or fluid intake.

• GI Tolerability: Across all options, the incremental monthly dosing schedule is strictly designed to mitigate gastrointestinal side effects (nausea, constipation, or diarrhea) as the body adapts to the medication.