Many different conditions can result in reduced production of pituitary hormones.Pituitary disease:Any disease of the pituitary can cause problems with hormone production. These problems include: pituitary mass lesions, pituitary surgery, empty sella, pituitary radiation, hemochromatosis, lymphocytic hypophysitis, Sheehan's syndrome, genetic diseases, pituitary abscess, pituitary apoplexy Hypothalamic disease:These disorders can also cause problems with the secretion of ADH which can cause diabetes insipidus. These problems include: hypothalmic mass lesions, hypothalamic radiation, hypothalmic infections Trauma to the brain:Head trauma which fractures the skull base can cause hypothalmic hormone dysfunction. The probability of pituitary function being affected is directly related to the severity of the injury. Strokes:These are rare strokes that affect the pituitary of hypothalamus. |